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NanoGroup strengthens its team: leading transplant and life science experts support innovative NanOX project

Prof. Ph. Eng. Tomasz Ciach has become the head of the Scientific Council established at NanoSanguis S.A. The newly established team will include leading experts in the fields of transplantology, pharmacy, veterinary medicine and biotechnology, who will support the company in the implementation of the NanOX organ perfusion system.

The Scientific Council of NanoSanguis made up of those associated with the NanOX project: prof. dr. hab. n. med. Maciej Kosieradzki, President of the Polish Transplantation Society and head of the project’s transplant team, and Ph. Eng. Jarosław Woliński, prof. D., associate professor at the Institute of Physiology and Animal Nutrition. Institute of Animal Physiology and Nutrition, named after Jan Kielanowski of the Polish Academy of Sciences. Jan Kielanowski of the Polish Academy of Sciences. This team, to be joined by more experts, is to support the implementation of the organ perfusion system project with knowledge and experience.

– The establishment of the Scientific Council is another key step in the implementation of the NanOX project. We believe that continued cooperation with experts, as well as maintaining the current pace of research, will allow us to sign a commercialization agreement with an industry partner next year. At the same time, it will be an important step in the company’s activities so that the NanOX system has a chance to reach hospitals around the world in the future – says Prof. Ciach, founder, board member of NanoGroup.

From sci-fi to the real world

In Poland, according to POLTRANSPLANT, in June 2024. for a kidney were waiting approx. 1170 patients, a liver more than 180, and there were almost 420 patients in line for a new heart. Although the number of operations performed involving transplantation of organs from deceased donors is increasing year by year – in 2023. a total of more than 1,800 were performed, while five years earlier it was approx. 1390 – there are still many patients who die before they receive a new organ.

– Transplantation is a struggle against time,” says Prof. Ciach and adds. – We have found a way to extend this time, and at the same time not only take care of the full functionality of the harvested organ, but even improve its condition.

The organ perfusion system designed by the Polish company is made up of the innovative NanOX perfusion fluid, the NanOX Recovery Box perfusion device and an advanced data analysis model and organ perfusion protocol.

In mid-July, NanoSanguis S.A. reported a successful kidney autotransplantation. The experiment involved taking one kidney from an animal after a 30-minute cardiac arrest, perfusing it for 12 hours with NanOX fluid and using the NanOX Recovery Box device under extracorporeal conditions in subnormothermia, ie. at a temperature of 25 degrees Celsius.

Wykazano jednocześnie, że system NanOX nie tylko przedłuża czas, w którym organ po pobraniu nadaje się do przeszczepu, ale dzięki wspieraniu procesu jego regeneracji, umożliwia wykorzystanie narządów nawet, gdy doszło do zatrzymania krążenia. To niezwykłe osiągnięcie, które może zrewolucjonizować transplantologię oraz stanowi odpowiedź na potrzeby społeczne. Jednym z głównych wyzwań, przed jakimi stoi współczesna medycyna, jest problem braku wystarczającej liczby narządów do przeszczepienia – według danych Światowej Organizacji Zdrowia w kolejce po nowy organ jest około pół miliona pacjentów na całym świecie. System NanOX otwiera zupełnie nowe możliwości nie tylko związane z dłuższym czasem przechowywania organów. Dzięki temu, że płyn wspiera proces regeneracji narządów, w przyszłości możliwe będzie pobieranie ich od znacznie większej grupy dawców, wśród których znaczną grupę stanowią osoby, u których doszło do śmierci z powodu zatrzymania akcji serca.

The solution developed by NanoGroup is a true revolution. The ability to keep organs in extracorporeal conditions for days and regenerate them at the same time would allow to significantly increase the number of transplants performed. This is an opportunity that tens of thousands of patients around the world have been waiting for for years,” explains Prof. Kosieradzki. Kosieradzki, a member of the newly appointed Scientific Council and head of one of the research teams.

Scientific Council members:

Prof. dr. hab. n. med. Maciej Kosieradzki is President of the Polish Transplant Society and a nationally and internationally recognized transplant surgeon (he obtained his specialization in 2009). He specializes in kidney, pancreas and liver transplants, using organs from healthy as well as deceased donors.

Since 2016. has served as head of the Department of General and Transplant Surgery at the Infant Jesus Clinical Hospital, although he has been with the institution itself much longer, since 1997. Importantly, the team of the Department of General and Transplant Surgery qualifies patients with organ failure for transplantation (including qualifying patients with severe lower urinary tract defects for kidney transplantation).

He has also been active in the international arena for many years. Since 2011, he has been a member of the Surgery Section and the European Board of Surgery in the European Union of Medical Specialists, Section of Surgery European Board of Surgery, and represents Poland in the European Society of Organ Transplantation (ESOT).

Dr. hab. n. biol. Eng. Jaroslaw Wolinski is an employee of the Jan Kielanowski Institute of Animal Physiology and Nutrition of the Polish Academy of Sciences, with which he has been affiliated since 2000, and has served on the unit’s Scientific Council since 2023. Among other things, he specializes in preclinical and clinical research with large animals, including in the field of transplantation.

In 1999, he graduated with a master’s degree in zootechnics from the Warsaw University of Life Sciences. Four years later, in 2003, he defended his doctoral thesis in agricultural sciences/zootechnics at the Jan Kielanowski Institute of Physiology and Nutrition of the Polish Academy of Sciences. In 2012, he was habilitated in the field of biological sciences/biology at the Faculty of Biology and Biotechnology of Maria Curie-Sklodowska University in Lublin. He is the author of numerous scientific papers and studies that have appeared in leading scientific titles.

Copyright © NanoGroup 2024

Paweł Ciach

Member of the Supervisory Board of NANOGROUP S.A.

Diplomat and specialist in the marketing and media industry. Graduate of the Department of International Relations at the National Institute of Oriental Languages and Civilizations in Paris and history and sociology at the Higher School of Social Sciences at the Faculty of History in Paris. Graduate of the Diplomatic Academy (Diplomatische Akademie) in Vienna and Postgraduate Management Studies at the Faculty of Management at the University of Warsaw. Worked as a journalist, publicist, reviewer, translator and foreign correspondent. Former advisor to the president of the board for media relations at the Agricultural Market Agency and president of the board of Press-Net. Public Relations trainer, among others at: Migut Media, Knowledge, ECU International, Advertising Academy Adam Śledański. He served as director of the board office of the Association of Organizations for the Employment of Disabled Persons and president of the board of the foundation “Niezależny. Fundacja na rzecz Nieprawni”. Lecturer at the Institute of Journalism of the Warsaw School of Advertising.

Jose Arrieta

Member of the Supervisory Board of NANOGROUP S.A.

Jose Arrieta is the former Chief Information Officer and Chief Data Officer of the United States Department of Health and Human Services. He oversaw $6.3B in IT investments, $800B in grants and $26B in Federal contracts in his last three years at HHS. He provided cyber security solutions for 174,000 people and a network that transacted with over 160 countries around the world. Jose led the creation and implementation of the largest public health surveillance capability in the United States during the pandemic and led the implementation of a national supervised machine learning effort to accurately distribute testing supplies and predict pandemic “hot spots” across the United States. He successfully defended the HHS network against multiple large scale nation state driven cyber-attacks. He led the first three implementations of blockchain technology in the public sector in the United States one of which was focused on reducing costs and speeding up procurement lifecycle. Jose was a cabinet level agency executive in the following positions: deputy assistant secretary for acquisition and grants, chief information officer, chief data officer, small business executive chief acquisition executive and senior procurement executive. Jose managed the largest contracting vehicle in the United States. He created and taught the first blockchain course (blockchain and cryptos) at Johns Hopkins University and taught business courses at University of Virginia and Prince George’s Community College. He founded small incubator called imagineeer when he left Government and works with customers and advises start-ups in the following markets: healthcare, food, energy, climate change, streaming and analytics, cybersecurity, artificial intelligence, and quantum computing. He is a member of the Navy Secretary’s Science and Technology Advisory Board.

Marek Borzestowski

Member of the Supervisory Board of NANOGROUP S.A.

For many years, President of the Management Board of NanoGroup, a holding company of biotechnology companies. Entrepreneur, manager and founder of many innovative companies with over 20 years of experience as co-owner and board member in leading Polish biotechnology, IT and e-commerce companies. After over a decade of work as president of the first internet portal in Poland – Wirtualna Polska, he founded the Polish-Israeli VC Giza Polish Ventures. Founder of the Sobieski Institute think tank, Startup Hub Poland Foundation. Member of supervisory boards in many innovative companies. Marek is a graduate of the Faculty of Management and Economics of the Gdańsk University of Technology, he also studied at the University of Wales in Great Britain. He conducted scientific research at the Center for Nuclear Research in Karlsruhe and the Gdańsk University of Technology.

Artur Olender

Member of the Supervisory Board of NANOGROUP S.A.

Investor, entrepreneur and financial advisor with over 28 years of professional experience. He managed the oldest Polish brokerage company – DM Penetrator S.A. Partner in Addventure and chairman of the supervisory boards of Intersport Polska S.A., Ailleron S.A., Archicom S.A., Sotis Sp. z o.o., OTC S.A. Former advisor to the Minister of Ownership Transformations and the Minister of the Treasury in privatization processes. Active participant in many environmental and legislative initiatives for the development of the Polish capital market. He participated in the implementation of dozens of projects to raise capital on the private and stock exchange market. He introduced to the stock exchange, among others, Mostostal Warszawa, Odlewnie Polskie, Poligrafia, WSiP, Polmos Białystok, Intersport, K2, Inteliwise, Cyfrowy Polsat, OT Logistic, Mercator Medical, Ailleron and Archicom. He studied at AGH and London Business School. Privately: windsurfer, sailor, skier, traveler, poet, composer and philanthropist.

Tadeusz Wesołowski

Member of the Supervisory Board of NANOGROUP S.A.

A well-known investor focused on companies from the medical and biotechnology industries. He has extensive professional experience in the healthcare sector. Founder of Prosper S.A., which is part of the NEUCA S.A. Capital Group – the leader of the pharmaceutical distribution market in Poland. Member of the supervisory boards of companies listed on the Warsaw Stock Exchange: NEUCA, Selvita and Braster. He is also involved in Venture Capital funds: Inovo and Experior. Doctor of Technical Sciences, graduate of the Warsaw University of Technology.

Robert Dziubłowski

Member of the Supervisory Board of NANOGROUP S.A.

Co-founder of Top Consulting S.A., one of the oldest consulting companies on the Polish market. He has over 25 years of international experience in the field of investment consulting, capital raising for companies, market acquisitions and company management. Long-time consultant to American financial organizations on Wall Street in New York, including those listed on the NASDAQ and NYSE stock exchanges. He advised, among others: Household International in preparing an acquisition strategy and obtaining a banking license in Poland, Wussler Group, a partner of Ted Turner Pictures in its attempt to take over NTV, the largest private television station in Russia, Eiffage Construction in the takeover of Mitex, the largest construction company at that time, Industrial Union of Donbas, an industrial group in Ukraine. Member, chairman and president of supervisory boards of many companies listed on the Warsaw Stock Exchange, including: Bauma S.A. (currently ULMA S.A.), Computerland Poland S.A. (currently Signity), PolAqua S.A. Co-founder of the Start-up Hub Poland Fund. Graduate of the Faculty of Journalism and Political Science at the University of Warsaw and International Relations at the University of Hawaii in Honolulu.

Jerzy Garlicki

President of the Supervisory Board of NANOGROUP S.A.

Medical doctor, also completed MBA, effective manager. Organizer of business model and company structures – experienced in building and developing companies and conducting restructuring processes of enterprises. In the past director and motivator of large companies and teams of people. A man recognizable as a leader in the Polish pharmaceutical industry. Member of the Supervisory Board of American Heart of Poland SA and President of WSiP SA. Previously President of Astra Zeneca Sp. z o.o., President of Fournier Polska Sp. z o.o., Sales Director of Pfizer Polska Sp. z o.o., Sales Director and Marketing Director of MSD Poland – also operating in the area of clinical trials.

Prof. Tomasz Ciach

Founder, Member of the Management Board of NANOGROUP S.A.

Nanotechnology expert. Professor at the Faculty of Chemical and Processing Engineering, Warsaw University of Technology, head of the Biotechnology and Bioprocessing Division. Author of two technologies that are already in production stage, 12 granted patents and over 50 publications. Founder of BioMedLab research group, consultant in numerous companies (AstraZeneca, Procter and Gamble, Reckit, Adamed, Balton, Galmed). Work on various aspects of Biomedical Engineering, mostly on biomedical nanotechnology, active coatings for medical implants, nanoparticles for cancer treatment, biodegradable and nonbiodegradable implants, bone and vascular prosthesis. He gives rare, but already brilliant example of how brave ideas become socially and financially valuable.

Piotr Mierzejewski

Vice President of the Management Board of NANOGROUP S.A.

Clinical pharmacology specialist, former advisor to the Minister of Health on drug policy. He negotiated Poland’s accession to the EU in the field of pharmacy, responsible for the implementation of EU directives in the field of pharmacy into the Polish legal system. Co-founder of the Office for Registration of Medicinal Products, Medical Devices and Biocidal Products. Owner of a consulting company cooperating with international pharmaceutical companies in the field of introducing new technologies to the Polish market.

Przemysław Mazurek

President of the Management Board of NANOGROUP S.A.

Associated with the health market since 2004. As Managing Director, he restructured and developed the most dynamically operating Medical Center in the Podkarpacie region, creating and setting new standards of customer service quality on the market. Co-creator of the first solution in Poland for online registration of medical appointments. Co-founder of the first and only Infertility Treatment Clinic (MEDICOR) in Podkarpacie, which he headed as the President until 2009. He was responsible for the development of health insurance in the PZU Group. As Vice President of PZU Pomoc S.A. created the largest medical TPA in Poland to handle health insurance. Co-founder of the first drug insurance in Poland. Since 2015, he has been active in the field of Wealth Management and advises on management and finance. A graduate of International Economic and Political Relations as well as Management and Marketing at the Warsaw School of Economics.

Przemysław Mazurek

President of the Management Board of NANOGROUP S.A.

Associated with the health market since 2004. As Managing Director, he restructured and developed the most dynamically operating Medical Center in the Podkarpacie region, creating and setting new standards of customer service quality on the market. Co-creator of the first solution in Poland for online registration of medical appointments. Co-founder of the first and only Infertility Treatment Clinic (MEDICOR) in Podkarpacie, which he headed as the President until 2009. He was responsible for the development of health insurance in the PZU Group. As Vice President of PZU Pomoc S.A. created the largest medical TPA in Poland to handle health insurance. Co-founder of the first drug insurance in Poland. Since 2015, he has been active in the field of Wealth Management and advises on management and finance. A graduate of International Economic and Political Relations as well as Management and Marketing at the Warsaw School of Economics.