Our polysaccharide nanoparticles utilize two targeting mechanisms:
- Drug Release Based on Intracellular pH Level – Nanoparticles enter the cell through endosomes. As a result of the low pH in the endosome, the bond breaks and the active substance is released.
- EPR Effect (Enhanced Permeability and Retention) – The rapid growth of tumor cells requires increased blood supply, resulting in greater permeability of blood vessels. Nanoparticles sized 100-200nm have a higher chance of reaching cancer cells.