5 March, 2025

Respiratory Gas Transport System

Breakthrough innovations

Respiratory Gas Transport System

  • Based on a new method of nanoformulation of perfluorocarbons.
  • Perfluorocarbons allow for high concentrations of oxygen and carbon dioxide in liquids.
  • Thanks to the innovative manufacturing method, nanoparticles maintain a stable distribution once dissolved in the liquid.
  • This can be used in various applications, particularly in replacing the function of red blood cells

 

NanOX System – A Breakthrough in Transplantology

  • The NanOX system is the first complete solution on the market dedicated to warm kidney perfusion before transplantation.
  • It allows for keeping the kidney alive outside the body, supporting metabolic processes.
  • It enables the use of organs with higher risk, particularly from donors after circulatory arrest (DCD).
  • It doubles the potential transplant market, reducing healthcare and social costs for long-term dialysis patients.
  • It consists of the NanOX 4 Kidney perfusion fluid, based on our respiratory gas transfer technology, the NanOX Recovery Box perfusion device, and a single-use perfusion kit.

NanOX System includes:

NanOX 4 Kidney Perfusion Fluid

Successful Autotransplantation

After a 30-minute ischemia simulation, a pig kidney was removed and subjected to a 12-hour ex vivo perfusion at 25°C using the NanOX fluid and device, followed by a successful autotransplantation back into the donor. A 14-day observation period ended successfully.

147 Hours of Ex-Vivo Storage

We achieved a breakthrough in organ storage research, maintaining an organ in a viable state outside the body for 147 hours – longer than any existing solution on the market.

 

NanOX 4 Kidney Perfusion Device

  • Defined fluid temperature range from 4°C to 37°C
  • Circulation condition simulation
  • Continuous data registration
  • Emergency power supply
  • Development platform for additional organs

Temporary Blood Substitute

  • NanoGroup is developing a new version of a temporary blood substitute.
  • Our developed nano-emulsion solves challenges that have been faced by perfluorocarbon-based products.
  • This is one of the largest unmet medical needs and a project with the potential to transform emergency medicine.

 

 

 

 

 

pp-thumbnail